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By Woodruff T.K.

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Apnoea of prematurity The physiological changes required to progress from foetus to neonate are large. There are complex physiological mechanisms that facilitate the transformation from dependence on maternal placental circulation to life as a separate stand-alone organism. Being born prematurely throws the evolved transformational process into disarray; previously physiologic reflexes become detrimental and certain reflexes needed for independent living have not yet developed. uk. 1521-6896/$ – see front matter Ó 2010 Elsevier Ltd.

A primer on Apnea of prematurity. Advances in Neonatal Care 2005; 5: 155–170. quiz 171–154. 6. Martin RJ, Wilson CG, Abu-Shaweesh JM & Haxhiu MA. Role of inhibitory neurotransmitter interactions in the pathogenesis of neonatal apnea: implications for management. Seminars in Perinatology 2004; 28: 273–278. *7. Abu-Shaweesh JM. Maturation of respiratory reflex responses in the fetus and neonate. Seminars in Neonatology 2004; 9: 169–180. 8. Eichenwald EC, Ungarelli RA & Stark AR. Hypercapnia increases expiratory braking in preterm infants.

Lönnqvist / Best Practice & Research Clinical Anaesthesiology 24 (2010) 309e321 321 72. Armitage EN. Caudal blocks in children. Anaesthesia 1979; 34: 396. 73. Mazoit JX & Lonnqvist PA. Local anaesthetics and their adjuncts. ). Hatch & Sumner’s textbook of paediatric anaesthesia. 3rd edn. Hodder Arnold, 2009, pp. 211e226. 74. Bartocci M, Lundeberg S, Lönnqvist PA. Local anesthesia via subcutaneous catheter after thoracotomy in premature infants. World Congress of Pediatric Pain, Vancouver, 2006 (abstract).

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Activin by Woodruff T.K.


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